Friday, September 3, 2021

I Have More Questions

I write on the interrelationships of the political, economic, and social spheres. So why do I write so much about COVID-19? It has to do with the effect this illness—and the response to it—have had on our freedoms, our economy, and our social interactions.

I’m interested in treatments—and I wonder why they aren’t more widely known. And I’d really like to know why they have been so often censored

And I’m interested in mandates. Especially when the things being mandated go against science and everything we’ve known about treating disease for over a century. This seems to me to be very much related to our freedoms and threatens to affect them even more. The very idea of a vaccine mandate—knowing what we know about this one—troubles me greatly. I’m in a category of should-hesitate-to-get-the-vaccine, according to the WHO. So does that mean I should be prevented from travel and entering certain places or doing certain things, like I’m a pariah? I’m a supposed danger to society because I have a preexisting health condition that puts me at greater personal risk but no added risk to society?

The more I look at this pandemic—as it becomes endemic—the more questions I have.

Dr. Peter McCullough answered questions recently,  updating us on current COVID-19 treatments. He made three main points:

·       The virus does not transmit asymptomatically. (Since June, no more asymptomatic testing.)

·       The Delta variant is not stopped by the vaccine.

·       Early treatment is needed.

Let’s cover the relatively good news first, combining early treatment news and lack of asymptomatic transmission.

 

TREATMENTS

Dr. McCullough offers some general suggestions. He says you should evaluate yourself and your children when you get up in the morning. It used to be that we’d go to work or school with what we thought was “just a cold.” Don’t do that now. Stay home. If you isolate yourself as soon as you have symptoms, that is much more effective at stopping the spread than either masks or lockdowns. If you haven’t yet experienced symptoms, you’re not going to spread the virus.

Dr. Peter McCullough in interview with Dr. Al Johnson
screenshot from here
The good news is that the FDA has given emergency use approval for hydroxychloroquine (HCQ—which should be given along with zinc and azithromycin) and ivermectin for COVID-19 treatment. (I have read contrary information on this, so it may be that the news hasn’t yet spread.) So doctors shouldn’t fear giving it as an early treatment. HCQ appears to have a better response to the Delta variant than ivermectin. But early treatment is key. One proviso Dr. McCullough mentioned is, for African-Americans, ask if they have the genetic deficiency G6PD, which causes a blood disorder called hemolytic anemia. In any other case, use HCQ. With pacemakers, with all different types of disorders; it’s safe. It has been proven in over 65 years of use. It’s similar to Benadryl or Seldane in safety. There are over 250 studies showing it’s safe and effective as the go-to drug for COVID-19. 

Children are generally safe and don’t need treatment (drugs). If they’re healthy to begin with, they’re likely to experience no more than general cold symptoms for a few days. Last year, worldwide, there were 300 child deaths reported as COVID-19; only one had been considered a healthy child.

However, if there’s a persistent fever, they could use a child-adjusted dose of aspirin for a few days (yes, aspirin, as you would for acute rheumatic fever). Also, if the child has asthma, budesonide is the COVID-19 treatment of choice. Or they may need an oral prednisone, or maybe a Z-pak (azithromycin, an antibiotic).

Because healthy children risk only a couple of days of cold-like symptoms, there is nothing to gain from vaccination. There is much greater risk to children from a vaccine than from the virus.

Nutraceuticals are helpful for everybody: zinc, Vitamin D, Vitamin C. Also, “there’s a polyphenol supplement called quercetin,” about 500 mg daily. Those are good for everybody.

The Delta variant is the mildest so far. (New fears are out now about the Mu variant; if it has gone as others, it is milder but more contagious. However, there’s also fear it may be more vaccine resistant. He didn't comment on this.)

When you notice symptoms, he suggests getting a Sofia test.  It’s not as sensitive as the PCR test, which means, when it shows up positive, the virus is really there. No false positives, which have been a persistent problem.

And there are a couple of surprising suggestions. He has learned from oral hygienists, who have long known how to prevent the spread of viruses, you can brush your teeth with yellow Listerine, and rinse your mouth with it. You could also use a dilute human-safe hydrogen peroxide, or an ozone nasal spray. 

A nasal saline irrigation helps a couple of times a day too. That’s a neti pot. (Use distilled water, not just purified water; the minerals in non-distilled water sting. But once you’ve dissolved in the little packet of saline to distilled water, it doesn’t sting anymore. Personal experience.) It not only rinses out allergens, but also viruses and other pathogens.

He didn’t go into great detail, but there’s a solution you can use (I’m not certain how) of 1 teaspoon bleach in dilution with 500cc water.

So, a nutraceutical bundle and nasal and oral hygiene make a difference in prevention.

The treatment protocols, he reminds us, can be found at AAPSonline.org and Truth for Health Foundation, which publishes an updated list of treating physicians. Also, Dr. Al Johnson, who interviewed Dr. McCullough, has a protocol for treating long haul COVID-19, available at CovidRecoveryTreatment.com.   

The very few telemed centers have been overtaxed lately. Dr. McCullough says we need to push doctors to treat. They’ve been afraid to treat, and may not be aware of the many treatment options, or changes in FDA approvals. Give them the protocols, and insist on early treatment.

Treatment is probably not necessary for the healthy under-50—unless and until their symptoms show severity. For the over 50 or those with co-morbidities, early treatment is called for, as soon as the illness is identified.

Monoclonal antibodies, as are being done all over Florida, are useful. Regeneron is a brand name. But Dr. McCullough suggests getting this done as an outpatient. Call ahead to the ER and order it, so that you remain an outpatient. And make sure the IV is administered slowly; it must take a full hour. Too quick an infusion leads to a cytokine storm, the very thing you’re trying to prevent.

Convalescent plasma is being phased out. The problem was, they didn’t separate the vaccinated from the unvaccinated when collecting blood; the vaccinated don’t have enough antibodies to be useful in the production of this treatment.

 

NATURAL IMMUNITY vs. VACCINATED IMMUNITY

Now for the questions that came up for me as I listened to Dr. McCullough and others.

He cited Israel, Singapore, and Iceland, where, during the latest surge, more than 75% of COVID-19 cases and 65% of those hospitalized are fully vaccinated. He concludes from that, it’s clear the vaccines are failing against the Delta variant. He said it’s possible, but unproven, that the vaccine helps mitigate against virulence. But there are patients dying who have been fully vaccinated.


Chart found in Epoch Times article, here.

Dr. McCullough notes the lack of attention for those who have had the illness and therefore have natural immunity. He says,

Once you’ve had it, you have full immunity. There’s never been a bona fide second case. Analysis by Murchu and colleagues in Ireland showed in 615,000 individuals, 11 studies, that even poorly defined cases that didn’t catch the original illness, if they had antibodies or some other indication that they’ve had it before, the chances of COVID-19 were way less than 1%. So, natural immunity is robust, complete, and durable. And it cannot be improved upon with vaccination.

I wondered about the “never been a bone fide second case” followed by the “way less than 1%.” While searching for the analysis by Eamon O. Murchu and colleagues, I came upon an article reprint, original by Daniel Horowitz for The Blaze, citing the Israel report in July. (And this week their report was verified by Bloomberg News. Incidentally, this fact check framed comparing getting immunity by getting ill or by getting the shots, and says getting ill is a riskier way of getting immunity. But that’s not the actual question. The real question is, for people who have natural immunity because they’ve already had the illness—219,017,517 globally as of today—is there any reason to also get the shots? And the answer is clearly no.)  

Israel National News reported: 

With a total of 835,792 Israelis known to have recovered from the virus, the 72 instances of reinfection amount to 0.0086% of people who were already infected with COVID.

By contrast, Israelis who were vaccinated were 6.72 times more likely to get infected after the shot than after natural infection, with over 3,000 of the 5,193,499, or 0.0578%, of Israelis who were vaccinated getting infected in the latest wave.

Recurring cases (those believed to be) are not zero; it’s 8.6 cases per 100,000. Almost none requiring hospitalization, and no deaths. Breakthrough cases (cases after vaccination) are still considerably lower than those with neither prior infection nor vaccination. But clearly the vaccine does not really prevent infection. In fact, now they’re not calling for vaccination to prevent infection; they’re calling for it to hopefully prevent serious infection. (Which, of course you could do with the nutraceuticals and other recommendations, just saying.)

In the article Horowitz offers Dr. McCullough’s more complete explanation of zero cases:

Despite the endless search by the media to find cases of severe reinfection, they have failed to find it. Dr. Peter McCullough, cardiologist and vice chief of medicine at Baylor University Medical Center in Dallas, Texas, told me in an interview that “there has never been a confirmed second infection beyond 90 days with similar or worse cardinal symptoms and confirmed PCR/Antigen/Sequencing test” in a case where the patient already had a well-documented case with acute illness. He notes that most database studies that attempt to quantify reinfection “are not sufficiently reliable to declare recurrent cases” and usually contain a false positive PCR on one or more occasions.

When I looked up the study and a couple of associated articles (such as this one), the explanation is that it’s difficult to differentiate between a new infection and persistent viral carriage (a sort of semi-dormant condition with occasional flare-ups, as is common in Epstein-Barr virus, for example). There would need to be a comparison between the genome sequencing of a banked sample from early in the illness and another sample at the time of what appears to be reinfection. That banking is almost never done, nor is the genome sequencing, because there is no reason other than to answer the question of whether it’s actually a reinfection or not in the rare instance when these cases turn up. In many “reinfection” cases, it’s often hard to determine whether the original infection was actually COVID-19, or a false positive test or misdiagnosis (or failure to accurately diagnose).

I’ve known of a number of people who say they have gotten it more than once. I know they believe so.  But my question is, did they really?


I came upon this comment in a Facebook group. Not someone I know.

Horowitz provides an explanation about the power of natural immunity from Idaho physician/researcher Dr. Ryan Cole:

Dr. Ryan Cole, a Mayo Clinic-trained pathologist who runs the largest independent laboratory in Idaho, explained to me how infection-induced immunity is much deeper and broader. “A natural infection induces hundreds upon hundreds of antibodies against all proteins of the virus, including the envelope, the membrane, the nucleocapsid, and the spike,” said Dr. Cole, who has spent the past 16 months examining and culturing SARS-CoV-2 specimens. “Dozens upon dozens of these antibodies neutralize the virus when encountered again. Additionally, because of the immune system exposure to these numerous proteins (epitomes), our T cells mount a robust memory, as well. Our T cells are the ‘marines’ of the immune system and the first line of defense against pathogens. T cell memory to those infected with SARSCOV1 is at 17 years and running still.”

However, in vaccine-induced immunity, according to Cole, “we mount an antibody response to only the spike and its constituent proteins.” He explains how this produces much fewer neutralizing antibodies, and “as the virus preferentially mutates at the spike, these proteins are shaped differently and antibodies can no longer ‘lock and key’ bind to these new shapes.”

Further down in the article he adds this additional explanation from Dr. Cole:

The media has focused incessantly on antibody levels and the observation that they often drop months after the infection; however, as with other viruses, that does not indicate waning immunity. “Yes, our antibody levels drop over time; however, scientifically, the memory B cells that make antibodies have been proven to be present in our lymph nodes and bone marrow,” explained Dr. Cole. “They are primed and ready to produce a broad array of antibodies upon viral pre-exposure. It would be physiologically, energetically impossible to maintain high antibody levels to all the pathogens we are constantly exposed to, and we would look like the ‘swollen Stay-Puft marshmallow man’ of lymph nodes, constantly, if the immune system were required to do that.”

This coincides with an explanation I heard from Dr. Mobeen Syed.   He was looking at this article and this study it related to.   He adds helpful little cartoon drawings to illustrate. 


Dr. Mobeen Syed explains about bone marrow plasma cells (BMPC) and long-term antibodies.
screenshot from here


So, what we know is that natural immunity gained from getting the virus and recovering is both long-lasting and robust. Immunity gained from the vaccines is somewhat helpful for a time, but less so to variants. And natural immunity is several times more powerful than vaccine immunity.

What did Israel do upon finding the vaccine was failing against the Delta virus? Decided to require more boosters, including for the previously infected. I’m baffled.

The reasons could be a difference in interpretation of the studies. Or it could be ignoring the studies for some other reason.

 

WHAT I WANT TO KNOW

I’ve been writing about treatments for COVID-19 since March 2020. While a lot of this information was censored for a long time, the truth has a way of seeping to the surface. It’s surprising to me that the standard treatment is still, “Stay home and rest until you’re sick enough for the hospital.” That makes no sense.

I’ve put a fair amount of faith in the treatments I’ve learned about. So, I’d like to know if they’re being used and people are still being hospitalized, or are these hospitalized patients still being deprived of early treatment?

We’ve just gone through our third surge, now waning I believe. By now I have known a number of people who’ve had the illness. Except for a couple overseas, I haven’t been closely acquainted enough to anyone hospitalized to ask the questions I want to know. I feel like I would be intruding into their privacy to ask these questions.

I’m not an investigative journalist. And I’m certainly not a medical researcher. But I have to wonder why someone doesn’t ask and get answers to the questions I have about treatments, about vaccine efficacy, and about natural immunity.

If I had the power to do it, I would ask the following questions of people hospitalized for COVID-19 (if the patient died or is a child, then a spouse, parent, or loved one could answer these questions for them):

THE SURVEY

1.     What was your experience when you first noticed symptoms?

a.     What were the symptoms you noticed?

b.     Did you get tested? On which day of symptoms? And on which day of symptoms did you get results? What type of test was it?

2.     Did you receive at-home treatment instructions when you got your test and/or results?

a.     What were you instructed to do?

b.     Were you prescribed or recommended to take any medications and/or supplements?

3.     Were there preventative steps you took prior to your illness (other than vaccination, which is asked below)? What were they? (Possibilities might include healthy diet and exercise, supplementing with Vitamin D, zinc, and/or Vitamin C; under a doctor’s care these might include a prophylactic dose of a drug such as hydroxychloroquine or ivermectin. Or you may have tried something not listed here.)

4.     Do you know where you were exposed to the illness? (by a particular person, in a particular setting, at work for example, or at an event?)

a.     Did anyone else in your household get the illness? Were their symptoms mild or required hospitalization? List the various persons and the severity of their illness (ex: spouse—hospitalized, teenage son—mild).

5.     On what day of symptoms did your situation worsen enough to require hospitalization?

a.     Describe the worsened/new symptoms.

6.     What was your sequence of treatments and their results in the hospital?

7.     How long were you hospitalized?

8.     How long until you were considered over the illness—no longer contagious, and no longer in danger of succumbing to symptoms?

9.     Did you have symptoms that persisted after your apparent recovery? Such as shortness of breath, heart palpitations, brain fog, fatigue.

a.     What symptoms continued and for how long (so far, if they are still present)?

b.     Did you have symptoms that began after you thought you had fully recovered? What were they? (For example, some healthy fit patients go back to full activity and then find themselves relapsing or having the varied symptoms of long-haul COVID-19.)

c.     What treatment did you receive for long-haul COVID-19 (persistent symptoms)?

10. What was your vaccination status?

a.     Unvaccinated?

b.     One shot but not second?

c.     Two shots, but not more than 2 weeks before onset of symptoms?

d.     Two shots from 2 weeks to 6 months or longer (how much longer?) prior to onset of symptoms?

e.     Two shots plus a booster shot?

11. Had you been diagnosed with COVID-19 before?

a.     If yes, go through the above questions for that infection as well.

                                             i.    Do you have certainty—based on symptoms and/or testing and doctor’s care—that what you had previously was definitely COVID-19?

                                           ii.    When did you have the previous illness (months, weeks, and/or days before your current illness)?

12. What is your age?

13. Do you have any co-morbidities? (Common ones are obesity, diabetes, active cancer, atrial fibrillation, COPD, dementia, heart disease, hypertension, chronic liver disease, chronic renal failure, stroke.)


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