Monday, April 6, 2020

Encouraging Words


I don’t like hearing, “You’re not good enough; you need to do more,” especially when it’s a group project. Like the one we’re all involved in.

We’ve been confined to home, with a few times venturing out to forage for food, for about 3 ½ weeks now—coincidentally how long we in our household have been confined because of Mr. Spherical Model’s broken ankle, which makes it easy to keep track. And we haven’t, until now, gotten anything like, “What a good job you’re doing! It’s working.” In fact, this week there’s extra pressure to add face-mask-wearing to the going out routine.

Also, someone asked Dr. Anthony Fauci the other day the question that we should have had on the table before shutting down the world economy: what has to happen before we can let up? Fauci’s answer was zero new cases and zero deaths.

This is why you don’t have experts make policy. Fauci’s side is the scientist side; he’s required (and requires himself) to give the absolute, scientific answer—as part of the information a decision-maker needs.

We don’t shut down the world economy indefinitely until there is no new incidence nor a single death. We didn’t shut it down for the flu, which causes 40,000+ deaths a year. We didn’t shut it down in the past for polio, or small pox, or measles. We didn’t shut it down for the Spanish flu in 1918—although that pandemic affected the economy on its own, and some areas were shut down. We didn’t shut it down for Ebola a few years ago.

Zero possible deaths is not a standard we typically base policy on. We don’t stop people from swimming, or boating, or hiking. We don’t stop people from driving. We don’t even stop people from driving over 25 mph, even though we can estimate how many more deaths will occur for each increment of higher speed. We set policy based on something more, which includes willingness of the people Because people need to make a living, go about our lives, and willingly face a certain level of risk.

So while Dr. Fauci is right about what he needs to say, policymakers also need a say. (We discussed this difference in thinking on March 30.)

For example, about hydroxychloroquine, Dr. Fauci points out that there have not been double-blind clinical studies to determine effectiveness, only anecdotal evidence. So he is not in a position to give the green light for that drug. But anecdotal evidence isn’t nothing.

Dr. Vladimir Zelenko,
interview with Rudy Giuliani March 26th,
screenshot from here
There’s a doctor, Dr. Vladimir Zelenko, a family practitioner in New York, interviewed by Rudy Giuliani on his show Common Sense, on March 26th, with some significant anecdotal evidence. (Bill Whittle shares a 15-minute clip of this interview on his CoronaSphere Lounge , Episode11, March 30th, which is where I saw it.)   

In New York, Dr. Zelenko has treated a plethora of coronavirus patients—699 by March 30th. He had been using a combination of hydroxycholoquine with zinc supplements, plus azithromycin. The combination of the three had worked in 100% of sick patients. He only gave the drug to patients already struggling with the virus or who were at very high risk, not the ones who were clearly going to get over it on their own without drugs. Of these moderately severe patients, zero moved into the more serious illness of Acute Respiratory Distress Syndrome, which requires intubation, and from which there’s only a 50% recovery rate. Zero of his patients have died. Three have needed hospitalization with pneumonia; zero needed intubation. The 3-drug protocol takes five days. It’s possible not all symptoms will be gone at that point, but the virus replication has been slowed to the point the body can fight it off without further complication.

Dr. Zelenko thinks that the hydroxycholoquine is not actually attacking the virus. Rather, the zinc is interfering with the virus’s replication process. But the zinc has trouble entering the cell without the hydroxycholoquine. Once the hydroxychloroquine creates a channel into the cell, the zinc enters and does its healing work against the virus. Meanwhile, the azithromycin, an antibiotic, is working on a secondary bacterial infection, which happens when the gunk builds up in the bronchial tubes and lungs.

All total, the treatment is about $20 per patient and can be done in an outpatient setting.

Dr. Zelenko’s results coincide with other doctors using the hydroxychloroquine. In France, hydroxychloroquine had been combined with azithromycin in the lab with 100% success. Doctors in France and South Korea, and also doctors in New York ICUs, were each using two of the three medicines, with moderate success. He used the combination of all three, with significant success.

Note that it was only March 19th when President Trump suggested that the FDA allow hydroxychloroquine to be used in this off-label way, in clinical trials, to treat the virus. Dr. Zelenko offers his evidence on March 26th, one week later. The speed with which we’re getting at ways to treat and test for this virus is remarkably swift.

So a policymaker can look at that, listen to Dr. Fauci, but then say, why not use this on people who need something and have nothing better to try? Would you take it, if it were you? Probably yes. And the more anecdotal evidence we get—despite the lack of a double-blind study—the more likely we are to say “definitely yes.”

[Speaking of “anecdotal" evidence, there’s this piece, possibly worth considering.] 

So, that’s how a policymaker thinks differently from a scientist. We need both. But the policymakers are the ones radically affecting our lives right now, while the scientists do their very important role in the background.

We were told to social distance at first. Then stay home, with nonessential businesses shut down, all of us hoping that doing this for a few weeks would make a big difference.

But it has been that long. And without testing of the whole population—and we need two kinds of tests: to find out who has the virus now, and to find out who has antibodies because they’ve already fought off the virus—we don’t know what’s working. In that black hole of missing data, we’re stuck at home with the economy crashing around us indefinitely.

So, is there another way to tell whether what we’re doing is working? It turns out there is.
I got this chart from Bill Whittle, who has been giving encouraging words lately. He got the info from Kinsa’s Healthweather.us.  

data on fevers, from Healthweather.us

This chart does not show Covid-19. It shows body temperatures. There are companies, such as Kinsa, that make “smart” thermometers. People take their temperature, and their information gets uploaded for mass data purposes. The data has been gathering for enough years that there’s a normal expected range for the months of the year. In our country, body temperatures rise during winter, coinciding with cold and flu season, and then go down to a summer low, and rise back up in the fall. So that’s the blue range on the chart.

If you look at the orange line, and the red dots, you can see the actual data compared to the expected data (the blue). Then look at the dates. When we started radically modifying our behavior, there’s a sharp decrease in body temperature—fewer fevers. That line pretty quickly drops below the expected level. Well below. Not only is the social distancing cutting down new fevers from coronavirus; it’s cutting down fevers from all sources to well below expected levels. In other words, what works to keep from transmitting coronavirus also works to keep from transmitting flu and colds, the typical causes of fever.

Then there’s another chart, showing places, with dates and events added—from the same source at Healthweather.us. This one compares Santa Clara, California, to Miami-Dade, Florida.

fever level comparisons of counties and California and Florida
screenshot from here

They have many of the same events happen, but with Florida most happen somewhat later. What you can see is that the drop off becomes significant after the community makes significant changes, with steepest drops after schools are closed, restaurants are closed, and stay-at-home orders are put in place.

Did something else happen, coinciding with those dates, following a similar pattern in different places, other than the social distancing we’ve been doing in reaction to the coronavirus? I don’t think so.

The evidence is strong that staying at home is having an effect.

Yay, us! We deserve a pat on the back. From ourselves, of course, since we don’t want anyone else getting close to us.

Keep up the good work! But not indefinitely. It’s not time to quit doing what we’re doing yet. But we need to be having a serious talk about when we can go back out—without causing a sudden resurgence, which would be a terrible outcome.

We could use a few miracles—pick any you like:

·       The virus miraculously disappears.

·       The virus greatly decreases in the summer months, affording us time to prepare for a second season of it in the fall—with all the testing and treatments we’ll need.
·       The virus is greatly weakened as it changes—a not uncommon mutation in viruses, which die off quickly when they kill their hosts, so they need to weaken in order to perpetuate.
·       A cure is developed, tested, and made standard for care.
·       Testing procedures—for both presence of virus and presence of antibodies—are quick, cheap, and widely available within the near future and for any future outbreak.
·       We’re so good at staying home and social distancing that the virus stops having hosts to spread to and dies a natural death.

This coming Friday, Good Friday, our Church invites everyone to join us in a worldwide fast. That means, typically, skipping two meals over twenty-four hours. (For example, you eat dinner Thursday evening, and then fast until dinner time Friday evening, when you can eat again.) Prayer during a fast can be more intentional, because you feel your weakness and thus your reliance on God. We hold a monthly fast, and donate the cost of the two meals to help the poor; feel free to do that. This is a special additional one. Note that, if your health doesn’t permit you to go that long without food, you can adjust your sacrifice to whatever you can do; your efforts and prayers will be acceptable to the Lord.

Illustration cred: Josh Asuncion
found on Facebook

In our modern world, there are so many ways we have managed to control the elements, we can sometimes forget our reliance on God. But I’ve had friends point out to me a couple of things. If the Lord wanted to use a calamity for good, how about having more time at home with families? And more, how about having people home together on Passover (Wednesday evening to Thursday evening), and even all Holy Week, including Easter Sunday?

We’ll miss getting together with our kids and grandkids for these days. But we’ve enjoyed some very sacred Sundays, meeting together as just the two of us. And we enjoyed a broadcast of a worldwide conference this past weekend. Spiritually, we’re doing better (dare I say it?)—because of the crisis.

Encouraging words are intended to instill courage. I’m glad we’re getting some of that. I pray it’s enough to fend off any more discouragement.

No comments:

Post a Comment